| Immunogen | PurifiedrecombinanthumanMARCKS;Epitopemappedtothecarboxyl-terminal. | 
| Clone | 2F12 | 
| Host | Mouse | 
| Specificity | MARCKS | 
| Isotype | IgG1 | 
| SpeciesReactivity |  | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | TheproteinencodedbythisgeneisasubstrateforproteinkinaseC.Itislocalizedtotheplasmamembraneandisanactinfilamentcrosslinkingprotein.PhosphorylationbyproteinkinaseCorbindingtocalcium-calmodulininhibitsitsassociationwithactinandwiththeplasmamembrane,leADIngtoitspresenceinthecytoplasm.Theproteinisthoughttobeinvolvedincellmotility,phagocytosis,membranetraffickingandmitogenesis. | 
| GeneSymbol | - MARCKS
 - 80K-L
 - MACS
 - PRKCSL
 - FLJ14368
 - phosphomyristin
 - MRACKS
 - PKCSL
 - FLJ90045
 
  | 
| PurificationMethod | Ascites | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P29966#MARCKSisthemostprominentcellularsubstrateforproteinkinaseC.Thisproteinbindscalmodulin,actin,andsynapsin.MARCKSisafilamentous(F)actincross-linkingprotein. SIZE:332aminoacids;31555Da PTM:PhosphorylationbyPKCdisplacesMARCKSfromthemembrane.ItalsoinhibitstheF-actincross-linkingactivity. SIMILARITY:SwissProt:P29966##BelongstotheMARCKSfamily. | 
| MolecularWeight | nonegiven |