| Immunogen | RecombinantextracellulardomainofmouseM-Cadherin | 
| Clone | clone12G4 | 
| Host | Mouse | 
| Specificity | M-Cadherin | 
| Isotype | IgG1κ | 
| SpeciesReactivity |  | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thisgeneisamemberofthecadherinsuperfamilyofgenes,encodingcalcium-dependentintercellularadhesionglycoproteins.Cadherinsconsistofanextracellulardomaincontaining5cadherindomains,atransmembraneregion,andaconservedcytoplasmicdomain.Transcriptsfromthisparticularcadherinareexpressedinmyoblastsandupregulatedinmyotubule-formingcells.Theproteinisthoughttobeessentialforthecontrolofmorphogeneticprocesses,specificallymyogenesis,andmayprovideatriggerforterminalmusclecelldifferentiation. | 
| GeneSymbol | CDH15CDH3myotubule-cadherincadherin-14Muscle-cadherinCDHMcadherin-3muscle-cadherinCadherin-14M-cadherinCDH14MCAD
 | 
| PurificationMethod | Thiophilicadsorptionandsizeexclusion | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P55291#Cadherinsarecalciumdependentcelladhesionproteins.Theypreferentiallyinteractwiththemselvesinahomophilicmannerinconnectingcells;cadherinsmaythuscontributetothesortingofheterogeneouscelltypes.M-cadherinispartofthemyogenicprogramandmayprovideatriggerforterminalmuscledifferentiation. SIZE:814aminoacids;88916Da
 SUBCELLULARLOCATION:Cellmembrane;Single-passtypeImembraneprotein.
 SIMILARITY:SwissProt:P55291##Contains5cadherindomains.
 | 
| MolecularWeight | Mr130kDa |