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Jackson/Biotin-SP (long spacer) AffiniPure F(ab")? Fragment Goat Anti-Human IgG, Fcγ fragment specific/0.5 ml/109-066-170

價格: ￥1147.50 市場價: 3060.00

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貨號: 109-066-170

品牌: Jackson

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- Based on immunoelectrophoresis and/or ELISA, the antibody reacts with the Fc portion of human IgG heavy chain but not with the Fab portion of human IgG.No antibody was detected against human IgM or IgA, or against non-immunoglobulin serum proteins.The antibody has been tested by ELISA and/or solid-phase adsorbed to ensure minimal cross-reaction with bovine, mouse and rabbit serum proteins, but it may cross-react with immunoglobulins from other species.
  F(ab")₂ fragment antibodies are generated by pepsin digestion of whole IgG antibodies to remove most of the Fc region while leaving some of the hinge region. F(ab")₂ fragments have two antigen-binding Fab portions linked together by disulfide bonds and therefore they are divalent. The average molecular weight is about 110 kDa. They are used for specific applications, such as to avoid binding of secondary antibodies to live cells with Fc receptors or to Protein A or Protein G.
  Biotin-SP (long spacer)
  Biotin-SP is our trade name for biotin with a 6-atom spacer positioned between biotin and the protein to which it is conjugated. When Biotin-SP-conjugated antibodies are used in enzyme immunoassays, there is an increase in sensitivity compared to biotin-conjugated antibodies without the spacer. This is especially notable when Biotin-SP conjugated antibodies are used with alkaline phosphatase-conjugated streptavidin. Apparently, the long spacer extends the biotin moiety away from the antibody surface, making it more accessible to binding sites on streptavidin. Biotinylated antibodies require an additional reagent for visualization. We offer streptavidin and Mouse Anti-Biotin conjugated to fluorophores and enzymes.
  Target: HumanHost: GoatAntibody Format: F(ab')? Fragment Specificity: IgG, Fcγ fragment specific
  Minimal Cross Reactivity: Bovine, Mouse, Rabbit Serum Proteins
  Conjugate: Biotin-SP (long spacer)Product Category: Fluorescent Protein Conjugates (R-PE, APC, and PerCP)Clonality: Polyclonal RRID: AB_2337643
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