Synonym:
Antibiotic S 7481F1,
Cyclosporin A,
Cyclosporine
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CAS Number 59865-13-3
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Empirical Formula (Hill Notation) C62H111N11O12
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Molecular Weight 1202.61
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Beilstein Registry Number 3647785
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MDL number MFCD00274558
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PubChem Substance ID 329749492
Properties:
Related Categories |
Analytical Standards,
Analytical/Chromatography,
Pharmacopeia & Metrological Institutes Standards,
USP Standards,
USP Standards C - D
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Description:
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia
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Other Notes
Sales restrictions may apply.
USP issued SDS can be found here
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Biochem/physiol Actions
A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.
Safety:
Symbol


GHS07, GHS08
Hazard statements
H302-H350-H360
Precautionary statements
P201-P280-P301 + P312 + P330-P308 + P313
RIDADR
NONH for all modes of transport