Synonym:
Frovatriptan succinate monohydrate,
Frovatriptan succinate,
R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate
Properties:
| Related Categories |
Analytical Standards,
Analytical/Chromatography,
Pharmacopeia & Metrological Institutes Standards,
USP Standards,
USP Standards E - F
|
Description:
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia
.
Other Notes
Sales restrictions may apply.
USP issued SDS can be found here
.
Biochem/physiol Actions
Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.
Safety: