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CAS Number 66893-81-0
Empirical Formula (Hill Notation) C10H14N2O2
Molecular Weight 194.23
Beilstein Registry Number 1453764
EC Number 266-512-3
MDL number MFCD00041022
PubChem Substance ID 24852894
Popular Documents: Specification Sheet (PDF) | FTIR (PDF)
| Related Categories | Analytical Reagents, Analytical/Chromatography, Building Blocks, C10, Chemical Synthesis, |
| InChI Key |
RNRMWTCECDHNQU-XYOKQWHBSA |
| assay | 99% |
| mp | 183-185 °C(lit.) |
| solubility | water: soluble 10 mg/mL clear, colorless to faintly yellow |
Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.
α-(4-Pyridyl N-oxide)-N-tert-butylnitrone was used as spin trapping agent to detect:
• the formation of hydroxyl radical adducts during decomposition of hydrogen peroxide in the presence of nickel (II) oligopeptides
• hydroxyl radicals and selenide radical anions
1 g in glass bottle
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