Synonym:
Natamycin,
Pimaricin
Properties:
Related Categories |
Analytical Standards,
Analytical/Chromatography,
E numbers (Food Additives),
E200–E299 (preservatives),
E235,
|
grade
|
analytical standard
|
InChI Key
|
NCXMLFZGDNKEPB-FFPOYIOWSA-N
|
product line
|
VETRANAL™
|
form
|
neat
|
shelf life
|
limited shelf life, expiry date on the label
|
application(s)
|
HPLC: suitable
|
|
gas chromatography (GC): suitable
|
format
|
neat
|
storage temp.
|
2-8°C
|
Description:
Biochem/physiol Actions
An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Natamycin is a polyene antibiotic that generally finds application as an antifungal agent as it lacks development of resistance and has a broad spectrum of activity. However, its mode of action is yet unclear, direct binding and isothermal titration calorimetry studies has revealed that natamycin binds specifically to ergosterol present in model membranes.
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Safety:
RIDADR
NONH for all modes of transport