Synonym:
(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
Properties:
Related Categories |
Analytical Standards,
Analytical/Chromatography,
Antibiotics Standards,
Pharmaceuticals, Illicit Drugs & Alcohol
|
grade
|
analytical standard
|
InChI Key
|
CTUAQTBUVLKNDJ-OBZXMJSBSA-N
|
product line
|
VETRANAL™
|
form
|
neat
|
shelf life
|
limited shelf life, expiry date on the label
|
application(s)
|
HPLC: suitable
|
|
gas chromatography (GC): suitable
|
format
|
neat
|
shipped in
|
wet ice
|
storage temp.
|
−20°C
|
Description:
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Meropenem has been used as a reference standard in an experiment conducted to investigate the effects on in vivo efficacy caused due to chemical differences in three generic products of meropenem.
Meropenem penetrates cell walls and binds to penicillin-binding protein targets. It acts against aerobes and anaerobes including E. coli, Klebsiella, Clostridium, Enterococcus sp. It is a common cause of mild transient aminotransferase elevations and can rarely result in clinically apparent, cholestatic liver injury.
Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.
General description
Meropenem trihydrate (Meropenem) is a broad-spectrum carbapenem with antibacterial properties. It inhibits cell wall synthesis in both gram-negative and gram-positive bacteria.
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Safety:
Symbol

GHS07
Hazard statements
H315-H319
Precautionary statements
P305 + P351 + P338
RIDADR
NONH for all modes of transport