Synonym:
(−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid,
Fosfomycin,
Phosphomycin disodium salt,
Phosphonomycin
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CAS Number 26016-99-9
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Empirical Formula (Hill Notation) C3H5Na2O4P
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Molecular Weight 182.02
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Beilstein Registry Number 4604425
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EC Number 247-409-2
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MDL number MFCD22741288
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PubChem Substance ID 329754806
Properties:
Related Categories |
Additional Standards,
Analytical Standards,
Analytical/Chromatography,
Antibiotics Standards,
Bacteriostatic,
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grade
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analytical standard
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InChI Key
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QZIQJIKUVJMTDG-JSTPYPERSA-L
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product line
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VETRANAL™
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form
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neat
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shelf life
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limited shelf life, expiry date on the label
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application(s)
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HPLC: suitable
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gas chromatography (GC): suitable
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format
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neat
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storage temp.
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2-8°C
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Description:
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Safety:
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR
NONH for all modes of transport