Synonym:
Limonoic acid 3,19:16,17 dilactone
Properties:
Related Categories |
Alphabetical Index of Phytochemical Standards,
Analytical Standards,
Analytical/Chromatography,
Citrus,
I - M,
|
grade
|
analytical standard
|
InChI Key
|
KBDSLGBFQAGHBE-MSGMIQHVSA-N
|
assay
|
≥90.0% (HPLC)
|
form
|
neat
|
shelf life
|
limited shelf life, expiry date on the label
|
application(s)
|
HPLC: suitable
|
|
gas chromatography (GC): suitable
|
format
|
neat
|
Description:
Biochem/physiol Actions
Limonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. It has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. It also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity.
General description
Limonin may be used in assays to quantify limonin in citrus products. It may also be used in other assays as a control, standard, or competitor or in studies on the physiology, metabolism, and biosynthesis of limonin.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Safety:
RIDADR
NONH for all modes of transport