Synonym:Macrogol4,000,PEGProperties:
RelatedCategories | Analytical/Chromatography,EssentialChemicals,MaterialsScience,PEGandOligoEthyleneGlycol,Pharmacopoeia, |
vapordensity | >1(vsair) |
vaporpressure | <0.01mmHg(20°C) |
form | solid |
autoignitiontemp. | 581 °F |
pharmacopeia | testingconformstoPharmacopeia |
molwt | molwt3500-4500 |
Description:
Application
Poly(ethyleneglycol)maybeusedinthefollowingstudies:
• Forthemodificationofproteinstoformtheconjugateshavingincreasedcirculatinglifeandreducedimmunogenicityandantigenicity.
• Preparationofhydrogelsusefulforthediffusioncontrolleddeliveryofproteins.
• Preparationofpoly(ethyleneglycol)dimethacrylate(PEGDM).
Generaldescription
Poly(ethyleneglycol)(PEG)isanon-toxicwater-solublepolymer.PEGtermisusedforthepolymerchainswithmolecularweightsbelow20000,whilepoly(ethyleneoxide)(PEO)referstothehighermolecularweightpolymers.PEGhasvariousbiomedicalapplications.Itformscomplexeswithα-cyclodextrins.EngineeringofPEGhydrogelparticlesbymesoporoussilica(MS)templatingmethodhasbeenreported.
Safety:
PersonalProtectiveEquipment
Eyeshields,Gloves,typeN95(US),typeP1(EN143)respiratorfilter
RIDADR
NONHforallmodesoftransport