Properties:
| Related Categories |
Additional Standards,
Amino Acid, Peptide & Protein Standards,
Analytical Standards,
Analytical/Chromatography,
Chromatography,
|
|
grade
|
analytical standard
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|
assay
|
≥98.0% (HPLC)
|
|
form
|
neat
|
|
shelf life
|
limited shelf life, expiry date on the label
|
|
application(s)
|
HPLC: suitable
|
|
|
gas chromatography (GC): suitable
|
|
impurities
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≤10 wt. % water
|
|
format
|
neat
|
|
storage temp.
|
2-8°C
|
Description:
Amino Acid Sequence
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.
Safety:
RIDADR
NONH for all modes of transport
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4000-520-616
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