Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | TyrosineHydroxylase(Phospho-Ser40)Antibody |
| Synonyms | THisoform3;THisoforma;TH-4;TY3H;TYH;Tyrosine3-hydroxylase;Tyrosine3-monooxygenase;tyrosinehydroxylase |
| Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanTyrosineHydroxylasearoundthephosphorylationsiteofSer40. |
| ImmunogenRange | 41-90 |
| Clonality | Polyclonal |
| ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:40000 |
| Specificity | TyrHydroxylase(Phospho-Ser40)AntibodydetectsendogenouslevelsofTyrHydroxylaseonlywhenphosphorylatedatSer40. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | TH |
| DatabaseLinks | GeneID: 7054 Swiss-Prot#: P07101 OMIM#: 191290/605407 Unigene#: Hs.435609/Hs.523414 |
| TargetModification | Phospho |
| ModificationSites | H:S71M:S40R:S40 |
| ApplicationImages |
| Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingTyrosineHydroxylase(Phospho-Ser40)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
| Image2 | WesternblotanalysisoflysatesfromRAW264.7cellstreatedwithUV30",usingTyrosineHydroxylase(Phospho-Ser40)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |