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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | Caspase 8 (Phospho-Ser347) Antibody |
| Synonyms | Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; Caspase-8 precursor; FADD-homologous ICE/CED-3- like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Ser347. |
| Immunogen Range | 313-362 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000 |
| Specificity | Caspase 8 (Phospho-Ser347) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Ser347. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | CASP8 |
| Database Links |
Gene ID: 841 Swiss-Prot #: Q14790 OMIM #: 211980/601763/607271 Unigene #: Hs.599762 |
| Target Modification | Phospho |
| Modification Sites | H:S347 R:S349 |
| Application Images | |
| Image 1 |
 Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using Caspase 8 (Phospho-Ser347) Antibody. The picture on the right is blocked with the phospho peptide. |
| Image 2 |
 Western blot analysis of lysates from Jurkat cells, using Caspase 8 (Phospho-Ser347) Antibody. The lane on the right is blocked with the phospho peptide. |
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