Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | Caspase8(Phospho-Ser347)Antibody |
| Synonyms | Apoptoticcysteineprotease;ApoptoticproteaseMch-5;CAP4;Caspase-8precursor;FADD-homologousICE/CED-3-likeprotease;FADD-likeICE;FLICE;ICE-likeapoptoticprotease5;ICE8;MACH;MCH5;MORT1-associatedCED-3homolog |
| Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanCaspase8aroundthephosphorylationsiteofSer347. |
| ImmunogenRange | 313-362 |
| Clonality | Polyclonal |
| ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:1000 |
| Specificity | Caspase8(Phospho-Ser347)AntibodydetectsendogenouslevelsofCaspase8onlywhenphosphorylatedatSer347. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | CASP8 |
| DatabaseLinks | GeneID: 841 Swiss-Prot#: Q14790 OMIM#: 211980/601763/607271 Unigene#: Hs.599762 |
| TargetModification | Phospho |
| ModificationSites | H:S347R:S349 |
| ApplicationImages |
| Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanlungcarcinoma,usingCaspase8(Phospho-Ser347)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
| Image2 | WesternblotanalysisoflysatesfromJurkatcells,usingCaspase8(Phospho-Ser347)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |