Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | Abl(Phospho-Tyr412)Antibody |
| Synonyms | ABL1;JTK7;Proto-oncogenetyrosine-proteinkinaseABL1;c-ABL;p150 |
| Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanAblaroundthephosphorylationsiteofTyr412. |
| ImmunogenRange | 361-410 |
| Clonality | Polyclonal |
| ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:1000 |
| Specificity | Abl(Phospho-Tyr412)AntibodydetectsendogenouslevelsofAblonlywhenphosphorylatedatTyr412. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | ABL1 |
| DatabaseLinks | GeneID: 25/27 Swiss-Prot#: P00519/P42684 OMIM#: 189980/608232/164690 Unigene#: Hs.431048/Hs.159472 |
| TargetModification | Phospho |
| ModificationSites | H:Y393/439M:Y393/439 |
| ApplicationImages |
| Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanlungcarcinoma,usingAbl(Phospho-Tyr412)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
| Image2 | WesternblotanalysisoflysatesfromCOS7cellstreatedwithAdriamycin0.5ug/ml24h,usingAbl(Phospho-Tyr412)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |