Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | CXCR4(Phospho-Ser339)Antibody |
Synonyms | C-X-Cchemokinereceptortype4;CXC-R4;CXCR-4;Stromalcell-derivedfactor1receptor;SDF-1receptor;Fusin;Leukocyte-derivedseventransmembranedomainreceptor;LESTR;LCR1;FB22;NPYRL;HM89;CD184antigen;CXCR4 |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanCXCR4aroundthephosphorylationsiteofSer339. |
ImmunogenRange | 303-352 |
Clonality | Polyclonal |
ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100IF:1:100~1:500ELISA:1:20000 |
Specificity | CXCR4(Phospho-Ser339)AntibodydetectsendogenouslevelsofCXCR4onlywhenphosphorylatedatSer339. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | CXCR4 |
DatabaseLinks | GeneID: 7852 Swiss-Prot#: P61073 OMIM#: 162643/193670 Unigene#: Hs.593413 |
TargetModification | Phospho |
ModificationSites | H:S339M:S346 |
ApplicationImages |
Image1 | ImmunofluorescenceanalysisofHeLacells,usingCXCR4(Phospho-Ser339)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
Image2 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingCXCR4(Phospho-Ser339)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
Image3 | WesternblotanalysisoflysatesfromHUVECcellstreatedwithetoposide25uM24H,usingCXCR4(Phospho-Ser339)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |