Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | CXCR4(Phospho-Ser339)Antibody |
| Synonyms | C-X-Cchemokinereceptortype4;CXC-R4;CXCR-4;Stromalcell-derivedfactor1receptor;SDF-1receptor;Fusin;Leukocyte-derivedseventransmembranedomainreceptor;LESTR;LCR1;FB22;NPYRL;HM89;CD184antigen;CXCR4 |
| Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanCXCR4aroundthephosphorylationsiteofSer339. |
| ImmunogenRange | 303-352 |
| Clonality | Polyclonal |
| ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100IF:1:100~1:500ELISA:1:20000 |
| Specificity | CXCR4(Phospho-Ser339)AntibodydetectsendogenouslevelsofCXCR4onlywhenphosphorylatedatSer339. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | CXCR4 |
| DatabaseLinks | GeneID: 7852 Swiss-Prot#: P61073 OMIM#: 162643/193670 Unigene#: Hs.593413 |
| TargetModification | Phospho |
| ModificationSites | H:S339M:S346 |
| ApplicationImages |
| Image1 | ImmunofluorescenceanalysisofHeLacells,usingCXCR4(Phospho-Ser339)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
| Image2 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingCXCR4(Phospho-Ser339)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
| Image3 | WesternblotanalysisoflysatesfromHUVECcellstreatedwithetoposide25uM24H,usingCXCR4(Phospho-Ser339)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |