Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | JAK3(Phospho-Tyr785)Antibody |
| Synonyms | JAK-3;JAK3;Januskinase3;L-JAK;Leukocytejanuskinase;kinaseJak3 |
| Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanJAK3aroundthephosphorylationsiteofTyr785. |
| ImmunogenRange | 751-800 |
| Clonality | Polyclonal |
| ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:1000 |
| Specificity | JAK3(Phospho-Tyr785)AntibodydetectsendogenouslevelsofJAK3onlywhenphosphorylatedatTyr785. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | JAK3 |
| DatabaseLinks | GeneID: 3718 Swiss-Prot#: P52333 OMIM#: 600173/600802 Unigene#: Hs.515247 |
| TargetModification | Phospho |
| ModificationSites | H:Y785M:Y996R:Y781 |
| ApplicationImages |
| Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingJAK3(Phospho-Tyr785)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
| Image2 | WesternblotanalysisoflysatesfromJurkatcells,usingJAK3(Phospho-Tyr785)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |