Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | JAK3(Phospho-Tyr785)Antibody |
Synonyms | JAK-3;JAK3;Januskinase3;L-JAK;Leukocytejanuskinase;kinaseJak3 |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanJAK3aroundthephosphorylationsiteofTyr785. |
ImmunogenRange | 751-800 |
Clonality | Polyclonal |
ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:1000 |
Specificity | JAK3(Phospho-Tyr785)AntibodydetectsendogenouslevelsofJAK3onlywhenphosphorylatedatTyr785. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | JAK3 |
DatabaseLinks | GeneID: 3718 Swiss-Prot#: P52333 OMIM#: 600173/600802 Unigene#: Hs.515247 |
TargetModification | Phospho |
ModificationSites | H:Y785M:Y996R:Y781 |
ApplicationImages |
Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingJAK3(Phospho-Tyr785)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
Image2 | WesternblotanalysisoflysatesfromJurkatcells,usingJAK3(Phospho-Tyr785)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |