Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | mTOR(Phospho-Thr2446)Antibody |
| Synonyms | FRAP;FRAP1;FRAP2;RAFT1;Rapamycintargetprotein;kinasemTOR |
| Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanmTORaroundthephosphorylationsiteofThr2446. |
| ImmunogenRange | 2412-2461 |
| Clonality | Polyclonal |
| ApplicationDilutions | WB:1:500~1:1000ELISA:1:10000 |
| Specificity | mTOR(Phospho-Thr2446)AntibodydetectsendogenouslevelsofmTORonlywhenphosphorylatedatThr2446. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | MTOR |
| DatabaseLinks | GeneID: 2475 Swiss-Prot#: P42345 OMIM#: 601231 Unigene#: Hs.338207 |
| TargetModification | Phospho |
| ModificationSites | H:T2446M:T2446R:T2446 |
| ApplicationImages |
| Image1 | WesternblotanalysisoflysatesfromNIH/3T3cellstreatedwithInsulin0.01U/ml15",usingmTOR(Phospho-Thr2446)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |