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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | mTOR (Phospho-Thr2446) Antibody |
| Synonyms | FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR |
| Immunogen | The antiserum was produced against synthesized peptide derived from human mTOR around the phosphorylation site of Thr2446. |
| Immunogen Range | 2412-2461 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 ELISA: 1:10000 |
| Specificity | mTOR (Phospho-Thr2446) Antibody detects endogenous levels of mTOR only when phosphorylated at Thr2446. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | MTOR |
| Database Links |
Gene ID: 2475 Swiss-Prot #: P42345 OMIM #: 601231 Unigene #: Hs.338207 |
| Target Modification | Phospho |
| Modification Sites | H:T2446 M:T2446 R:T2446 |
| Application Images | |
| Image 1 |
 Western blot analysis of lysates from NIH/3T3 cells treated with Insulin 0.01U/ml 15', using mTOR (Phospho-Thr2446) Antibody. The lane on the right is blocked with the phospho peptide. |
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