Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | p53(Phospho-Ser376)Antibody |
| Synonyms | AntigenNY-CO-13;Cellulartumorantigenp53;Phosphoproteinp53;TP53;tumorproteinp53;Tumorsuppressorp53 |
| Immunogen | Theantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanp53aroundthephosphorylationsiteofSer376. |
| ImmunogenRange | 344-393 |
| Clonality | Polyclonal |
| ApplicationDilutions | IHC:1:50~1:100ELISA:1:1000 |
| Specificity | p53(Phospho-Ser376)Antibodydetectsendogenouslevelsofp53onlywhenphosphorylatedatSer376. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | TP53 |
| DatabaseLinks | GeneID: 7157 Swiss-Prot#: P04637 OMIM#: 133239/151623/161550/191170/202300/211980/260500/275355 Unigene#: Hs.654481 |
| TargetModification | Phospho |
| ModificationSites | H:S376M:S370R:S374 |
| ApplicationImages |
| Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingp53(Phospho-Ser376)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |