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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | Gab2 (Phospho-Ser623) Antibody |
| Synonyms | GRB2-associated-binding protein 2; Growth factor receptor bound protein 2-associated protein 2; GRB2-associated binder 2; pp100; KIAA0571 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Gab2 around the phosphorylation site of Ser623. |
| Immunogen Range | 589-638 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000 |
| Specificity | Gab2 (Phospho-Ser623) Antibody detects endogenous levels of Gab2 only when phosphorylated at Ser623. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | GAB2 |
| Database Links |
Gene ID: 9846 Swiss-Prot #: Q9UQC2 OMIM #: 606203 Unigene #: Hs.429434 |
| Target Modification | Phospho |
| Modification Sites | H:S623 M:S612 R:S612 |
| Application Images | |
| Image 1 |
 Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Gab2 (Phospho-Ser623) Antibody. The picture on the right is blocked with the phospho peptide. |
| Image 2 |
 Western blot analysis of lysates from HepG2 cells treated with PMA 125ng/ml 30', using Gab2 (Phospho-Ser623) Antibody. The lane on the right is blocked with the phospho peptide. |
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