The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
FHIT (Phospho-Tyr114) Antibody
Synonyms
AP3A hydrolase; AP3AASE; Bis(5'-adenosyl)-triphosphatase; Bis(5'-adenosyl)-triphosphatease; Dinucleosidetriphosphatase; Fragile histidine triad protein
Immunogen
The antiserum was produced against synthesized peptide derived from human FHIT around the phosphorylation site of Tyr114.
Immunogen Range
80-129
Clonality
Polyclonal
Application Dilutions
IHC: 1:50~1:100 ELISA: 1:40000
Specificity
FHIT (Phospho-Tyr114) Antibody detects endogenous levels of FHIT only when phosphorylated at Tyr114.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
FHIT
Database Links
Gene ID: 2272 Swiss-Prot #: P49789
OMIM #: 144700/601153 Unigene #: Hs.655995
Target Modification
Phospho
Modification Sites
H:Y114
Application Images
Image 1
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using FHIT (Phospho-Tyr114) Antibody. The picture on the right is blocked with the phospho peptide.