| Immunogen | Syntheticpeptidecorrespondingtoaminoacids320-341ofhumanArp2.Theimmunogensequenceis100%identicalinmouse,rat,Xenopus,andchicken. | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Rabbit | 
| Specificity | RecognizesArp2(Actin-relatedprotein2).Arp2belongstotheArp2/3complex,which,whenstimulatedbyWASp/Scarproteins,nucleatesactinpolymerizationfromthesidesofpre-existingactinfilaments.TheevolutionarilyconservedArp2/3complexincludesArp2,Apr3,p41-Arc,p34-Arc,p21-Arc,p20-Arcandp16-Arc. | 
| SpeciesReactivity |  | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thespecificfunctionofthisgenehasnotyetbeendetermined;however,theproteinitencodesisknowntobeamajorconstituentoftheARP2/3complex.Thiscomplexislocatedatthecellsurfaceandisessentialtocellshapeandmotilitythroughlamellipodialactinassemblyandprotrusion.Twotranscriptvariantsencodingdifferentisoformshavebeenfoundforthisgene. | 
| GeneSymbol |  | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P61160#FunctionsasATP-bindingcomponentoftheArp2/3complexwhichisinvolvedinregulationofactinpolymerizationandtogetherwithanactivatingnucleation-promotingfactor(NPF)mediatestheformationofbranchedactinnetworks.Seemstocontactthepointedendofthedaughteractinfilament. SIZE:394aminoacids;44761Da
 SUBUNIT:ComponentoftheArp2/3complexcomposedofARP2,ARP3,ARPC1B/p41-ARC,ARPC2/p34-ARC,ARPC3/p21-ARC,ARPC4/p20-ARCandARPC5/p16-ARC.
 SUBCELLULARLOCATION:Cytoplasm,Cytoskeleton.
 SIMILARITY:SwissProt:P61160##Belongstotheactinfamily.ARP2subfamily.
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