| Immunogen | A22aminoacidpeptidesequencemappingtothe1stextracellulardomainofratNET. | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Rabbit | 
| Specificity | SpecificforNorepinephrineTransporter(NET).NorepinephrineTransporterisa617aminoacidlongintegralmembraneproteinbelongingtotheSodium:NeurotransmitterSymporterfamily(Brussetal.1995;Melikianetal.1994;Pacholczyketal.1991)Theimmunogenpeptideshowsnosignificanthomologywithotherotherknownproteins. | 
| SpeciesReactivity |  | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | TheSLC6A2geneencodesanorepinephrine(noradrenaline)transporter,whichisresponsIBLeforreuptakeofnorepinephrineintopresynapticnerveterminalsandisaregulatorofnorepinephrinehomeostasis(Kimetal.,2006[PubMed17146058]).[suppliedbyOMIM] | 
| GeneSymbol |  | 
| PurificationMethod | ImmunoAffinityPurified | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P23975#Aminetransporter.Terminatestheactionofnoradrenalinebyitshighaffinitysodium-dependentreuptakeintopresynapticterminals. SIZE:617aminoacids;69332Da
 SUBUNIT:InteractswithPRKCABP.
 SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
 DISEASE:SwissProt:P23975#DefectsinSLC6A2areacauseoforthostaticintolerance(OI)[MIM:604715].OIisasyndromecharacterizedbylightheadedness,fatigue,alteredmentationandsyncope.Itisassociatedwithposturaltachycardia.Plasmanorepinephrineconcentrationisabnormallyhigh.
 SIMILARITY:SwissProt:P23975##Belongstothesodium:neurotransmittersymporter(SNF)family.
 MISCELLANEOUS:Thisproteinisthetargetofpsychomotorstimulantssuchasamphetaminesorcocaine.
 | 
| MolecularWeight | 80&54kDa |