| Immunogen | Syntheticpeptidecorrespondstosequencesurroundingthephosphoserine515siteofratMunc-18. | 
| Host | Rabbit | 
| Specificity | Munc-18,phosphoSerine515.Theantibodyrecognizesaproteinof~65kDacorrespondingtoMunc-18,phosphoSerine515inlysatesfromratcortex.Immunolabelingisblockedbythephosphopeptideusedastheimmunogenbutnotthecorrespondingnon-phosphopeptide. | 
| SpeciesReactivity |  | 
| SpeciesReactivityNote | Theimmunogenhas100%homologywithhuman,mouse,non-humanprimates,bovine,canine,chickenandXenopus. | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| GeneSymbol |  | 
| Modifications |  | 
| PurificationMethod | ImmunoAffinityPurified | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P61765#Mayparticipateintheregulationofsynapticvesicledockingandfusion,possIBLythroughinteractionwithGTP-bindingproteins.Essentialforneurotransmissionandbindssyntaxin,acomponentofthesynapticvesiclefusionmachineryprobablyina1:1ratio.Caninteractwithsyntaxins1,2,and3butnotsyntaxin4.Mayplayaroleindeterminingthespecificityofintracellularfusionreactions. SIZE:594aminoacids;67569Da
 SUBCELLULARLOCATION:Cytoplasm.Membrane;Peripheralmembraneprotein.
 TISSUESPECIFICITY:Brainandspinalcord.Highlyenrichedinaxons.
 SIMILARITY:SwissProt:P61765##BelongstotheSTXBP/unc-18/SEC1family.
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