| Immunogen | GSTfusionproteinfromratstargazin,cytoplasmicdomain. | 
| Host | Rabbit | 
| Specificity | Stargazin[Stargazin-likeTARP(transmembraneAMPAreceptorregulatoryprotein)].ByWesternblottheantibodyrecognizesbandsat~35kDaand~55kDaonTritonsolublefractionofratbrain.TheantibodyreactsdominantlywithTARPgamma-8andweaklywithgamma-3andgamma-4.Stargazinisexpressedstronglyinthehippocampusandcerebellum. | 
| SpeciesReactivity |  | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | L-typecalciumchannelsarecomposedoffivesubunits.Theproteinencodedbythisgenerepresentsoneofthesesubunits,gamma,andisoneofseveralgammasubunitproteins.Itisanintegralmembraneproteinthatisthoughttostabilizethecalciumchannelinaninactive(closed)state.Thisproteinissimilartothemousestargazinprotein,mutationsinwhichhavebeenassociatedwithabsenceseizures,alsoknownaspetit-malorspike-waveseizures.ThisgeneisamemberoftheneuronalcalciumchannelgammasubunitgenesubfamilyofthePMP-22/EMP/MP20family. | 
| GeneSymbol | CACNG2stargazinMGC138504MGC138502
 | 
| PurificationMethod | ImmunoAffinityPurified | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:Q9Y698#Thoughttostabilizethecalciumchannelinaninactivated(closed)state. SIZE:323aminoacids;35966Da
 SUBUNIT:TheL-typecalciumchanneliscomposedoffivesubunits:alpha-1,alpha-2/delta,betaandgamma.InteractswiththePDZdomainsofDLG4/PSD-95andDLG1/SAP97.MayinteractwithGOPC(Bysimilarity).
 SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
 TISSUESPECIFICITY:Brain.
 PTM:PhosphorylationofThr-321impairsinteractionwithDLG1andDLG4.
 SIMILARITY:SwissProt:Q9Y698##BelongstothePMP-22/EMP/MP20family.CACNGsubfamily.
 |