當前位置： Millipore >>> Millipore/CBL1512 | Anti-Integrin αM [CD11b] Antibody, clone OX-42/CBL1512/500 µg

Millipore/CBL1512 | Anti-Integrin αM [CD11b] Antibody, clone OX-42/CBL1512/500 µg

價格: ￥4068.00 市場價: 6780.00

打印產品信息

貨號: CBL1512

品牌: Millipore

規格

默認

數量

庫存(0)

特別提示

代購產品：無質量問題不接受退換貨，下單前請仔細核對信息。
下單后請及時聯系客服核對商品價格，訂單生效后再付款。

立即購買加入購物車

收藏商品

資深產品顧問

咨詢顧問

全國免費服務熱線

4000-520-616

自營商城一站式服務
廠家直采剔除溢價
品質甄選正品保證
嚴控流程只做188精品
極速物流如約送貨

詳情
使用說明
常見問題

Description
CatalogueNumber	CBL1512
BrandFamily	Chemicon®
TradeName	Chemicon
Description	Anti-IntegrinαM[CD11b]Antibody,cloneOX-42
AlternateNames	CD11b
BackgroundInformation	IntegrinalphaM/beta2isimplicatedinvariousadhesiveinteractionsofmonocytes,macrophagesandgranulocytesaswellasinmediatingtheuptakeofcomplement-coatedparticles.ItisidenticalwithCR3,thereceptorfortheiC3bfragmentofthethirdcomplementcomponent.ItprobablyrecognizestheR-G-DpeptideinC3b.IntegrinalphaM/beta2isalsoareceptorforfibrinogen,factorXandICAM1.ItrecognizesP1andP2peptidesoffibrinogengammachain.

ProductInformation
Format	Purified
Control	Braintissue
Presentation	Themonoclonalispresentedinphosphatebufferedsalinecontaining10mMsodiumazide.

StorageandShippingInformation
StorageConditions	Forusewithin1monthofpurchasestoreat+4°C,forlongtermstoragealiquotantibodyintosmallvolumesandstoreat-20°C.

Applications
Application	DetectIntegrinαM[CD11b]usingthisAnti-IntegrinαMCD11bAntibody,cloneOX-42validatedforuseinFC,IH,IH(P)&IP.
KeyApplications	FlowCytometry Immunohistochemistry Immunohistochemistry(Paraffin) Immunoprecipitation
ApplicationNotes	Flowcytometry Immunohistochemicalstudiesofratfreshfrozentissuesectionsandparaffin-embeddedtissuesectionsfollowingeitherperiodate-lysine-paraformaldehyde(PLP)fixation,oracetone.WorksonverylightlyPFAfixed,frozentissues.(perfusiononly4%PFA10-15"nopost-fix). Immunoprecipitation:userabbitanti-mouseoranti-mouseIgGbeadforcaptureonly.TheuseofproteinAorproteinGisnotrecommended. Optimalworkingdilutionsmustbedeterminedbytheenduser.

BIOLOGicalInformation
Immunogen	Ratperitonealmacrophages
Clone	OX-42
Concentration	PleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
Host	Mouse
Specificity	Recognizesmostmacrophages(includingresidentperitonealandactivatedmacrophages),kupffercells,butonlyabout35%ofalveolarmacrophages.Theantibodyalsolabelsdendriticcellsextensively,granulocytesandcellswiththemorphologyofmicrogliainbrain.Theantibodyprecipitatesthreepolypeptidesof150,103and95KDa.TheantibodyinhibitscomplementmediatedrosettesandisprobablytheratequivalentofthehumanreceptorforIC3bcalledCR3. FUSIONPARTNER:NSOmyelomacellline.
Isotype	IgG2a
SpeciesReactivity	Rat
AntibodyType	MonoclonalAntibody
EntrezGeneNumber	NM_000632.3
EntrezGeneSummary	ThisgeneencodestheintegrinalphaMchain.Integrinsareheterodimericintegralmembraneproteinscomposedofanalphachainandabetachain.ThisI-domaincontainingalphaintegrincombineswiththebeta2chain(ITGB2)toformaleukocyte-specificintegrinreferredtoasmacrophagereceptor1("Mac-1"),orinactivated-C3b(iC3b)receptor3("CR3").ThealphaMbeta2integrinisimportantintheadherenceofneutrophilsandmonocytestostimulatedendothelium,andalsointhephagocytosisofcomplementcoatedparticles.SomeintegrinalphaMproteinscontainaninsertedaminoacid(Q,betweenAApositions499and500)resultingfroma3bpshiftinaspliceacceptorthatinsertsthecodonCAG;receptorswithorwithouttheextraaminoacidarefunctionallyindistinguishable
GeneSymbol	ITGAM MO1A CD11b MAC1A CD11B MAC-1 CR3A MGC117044
PurificationMethod	ProteinAPurfied
UniProtNumber	P11215
UniProtSummary	FUNCTION:SwissProt:P11215#Integrinalpha-M/beta-2isimplicatedinvariousadhesiveinteractionsofmonocytes,macrophagesandgranulocytesaswellasinmediatingtheuptakeofcomplement-coatedparticles.ItisidenticalwithCR-3,thereceptorfortheiC3bfragmentofthethirdcomplementcomponent.ItprobablyrecognizestheR-G-DpeptideinC3b.Integrinalpha-M/beta-2isalsoareceptorforfibrinogen,factorXandICAM1.ItrecognizesP1andP2peptidesoffibrinogengammachain. SIZE:1152aminoacids;127179Da SUBUNIT:Heterodimerofanalphaandabetasubunit.Alpha-Massociateswithbeta-2. SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:Predominantlyexpressedinmonocytesandgranulocytes. DOMAIN:SwissProt:P11215TheintegrinI-domain(insert)isaVWFAdomain.IntegrinswithI-domainsdonotundergoproteasecleavage. SIMILARITY:Belongstotheintegrinalphachainfamily.&Contains7FG-GAPrepeats.&Contains1VWFAdomain.

PhysicochemicalInformation

Dimensions

MaterialsInformation

MaterialsInformation

售后保障

螞蟻淘生物188，秉承螞蟻淘一貫的嚴謹態度，由螞蟻淘公司專業人員負責品控、采購、物流、銷售、售后，保障正品優質。以“快速好省，為科研提供好產品、好價格”為理念，直接鏈接原廠家，從全國各地原制造商嚴格挑選188款科研精品，剔除品牌溢價，188生物新電商，把好的產品帶給科研！? 力求給你最優質的商品。

Q：生物188產品正品保障嗎？
A：生物188質量把控人員具有十年的從業經驗，在業界享有良好的口碑；自營商城，直接從廠家采購，自己的團隊負責國際物流和清關，中間沒有第三方，所有流程嚴格把控，100%保證正品，假一罰十。

Q：下單后可以修改訂單嗎？
A：下單后的商品付款之前可以修改；訂單付款成功，需要聯系我們客服進行修改；客服電話：4000-520-616

Q：可以開發票嗎？
A：本網站所售商品都是正規清關，均開具16%正規發票，發票金額含配送費金額，另有說明的除外。

Q：商品幾天可以發貨？
A：生物188商品，全部現貨銷售，付款后即可發貨,一般一周內送達！

Q：如何聯系商家？
A：有任何問題夠可以電話咨詢我們，全國24小時免費服務熱線：4000-520-616 或聯系我們的在線客服QQ：1570468124

Q：收到的商品少了/發錯了怎么辦？
A：同個訂單購買多個商品可能會分為一個以上包裹發出，可能不會同時送達，建議查看訂單詳情是否是部分發貨狀態；如未收到，可聯系在線客服或者致電4000-520-616。

Q：退換貨/維修需要多長時間？
A：一般情況下，退貨處理周期為客戶收到產品一個月內（以快遞公司顯示簽收時間為準），包裝規格、數量、品種不符，外觀毀損、短缺或缺陷，請在收到貨24小時內申請退換貨；特殊商品以合同條款為準。

24小時熱銷榜

Jackson/Peroxidase AffiniPure Goat Anti-Mouse IgG (H+L)/2.0 ml/115-035-003
￥830.00
Jackson/Peroxidase AffiniPure Goat Anti-Rabbit IgG (H+L)/2.0 ml/111-035-003
￥830.00
Qubit? dsDNA BR Assay Kit Q32853現貨
￥2000.00
Parafilm M封口膜/PM996/4x125/整箱
￥1296.00

Millipore/CBL1512 | Anti-Integrin αM [CD11b] Antibody, clone OX-42/CBL1512/500 µg

客戶服務

何為188

關注188微信公眾號