| Immunogen | 12aminoacidpeptideoftheC-terminusofhGLUT-1{LFHPLGADSQV}conjugatedtoKLH | 
| Epitope | C-terminus | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Rabbit | 
| Specificity | Specificforhumanglucosetransporter1frommuscleandadiposetissue.Doesnotcross-reactwithGLUT-4.Themolecularweightoftheglucosetransporterprecipitatedbytheserumisapproximately46kDa. | 
| SpeciesReactivity |  | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Glucosetransportersareintegralmembraneglycoproteinsinvolvedintransportingglucoseintomostcells.GLUT1isamajorglucosetransporterinthemammalianblood-brainbarrier.Itispresentathighlevelsinprimateerythrocytesandbrainendothelialcells.[suppliedbyOMIM] | 
| GeneSymbol | SLC2A1GLUT-1MGC141896GLUT1MGC141895GLUT
 | 
| PurificationMethod | ImmunoAffinityPurified | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P11166#Facilitativeglucosetransporter.ThisisoformmayberesponsIBLeforconstitutiveorbasalglucoseuptake.Hasaverybroadsubstratespecificity;cantransportawiderangeofaldosesincludingbothpentosesandhexoses. SIZE:492aminoacids;54084Da
 SUBCELLULARLOCATION:Cellmembrane;Multi-passmembraneprotein(Bysimilarity).Melanosome.Note=Localizesprimarilyatthecellsurface(Bysimilarity).IdentifiedbymassspectrometryinmelanosomefractionsfromstageItostageIV.
 TISSUESPECIFICITY:Expressedatvariablelevelsinmanyhumantissues.
 PTM:PhosphorylateduponDNAdamage,probablybyATMorATR.
 DISEASE:SwissProt:P11166#DefectsinSLC2A1arethecauseofautosomaldominantGLUT1deficiencysyndrome[MIM:606777].Thisdiseasecausesadefectinglucosetransportacrosstheblood-brainbarrier.Itischaracterizedbyinfantileseizures,delayeddevelopment,andacquiredmicrocephaly.
 SIMILARITY:SwissProt:P11166##Belongstothemajorfacilitatorsuperfamily.Sugartransporter(TC2.A.1.1)family.Glucosetransportersubfamily.
 | 
| MolecularWeight | 46kDa |