Synonym:
Aminoacetic acid,
Aminoethanoic acid,
Glycocoll
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CAS Number 56-40-6
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Linear Formula NH2CH2COOH
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Molecular Weight 75.07
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Beilstein Registry Number 635782
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EC Number 200-272-2
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MDL number MFCD00008131
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PubChem Substance ID 24895210
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eCl@ss 32160406
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Popular Documents: Specification Sheet (PDF) | FTNMR (PDF)
Properties:
Related Categories |
Amino Acids,
Analytical/Chromatography,
Biochemicals and Reagents,
Pharmacopoeia,
Pharmacopoeia A-Z,
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Quality Level
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GMP-COMPENDIA
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biological source
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from non-animal source
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grade
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EP
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JP
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USP
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InChI Key
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DHMQDGOQFOQNFH-UHFFFAOYSA-N
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product line
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PharmaGrade
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assay
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≥98.5%
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form
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crystalline powder
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mfr. no.
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Ajinomoto
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impurities
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endotoxin, heavy metals, trace metals, residual solvents, tested
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pH
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5.9-6.4
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pKa (25 °C)
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2.35
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mp
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240 °C (dec.)(lit.)
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solubility
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H2O: 100 mg/mL
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UV absorption
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λ: 260 nm Amax: ≤0.04
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λ: 260 nm Amax: -0.006
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λ: 280 nm Amax: ≤0.04
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λ: 280 nm Amax: -0.003
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suitability
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suitable for cell culture
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suitable for manufacturing use
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foreign activity
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cytotoxicity, tested
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Gene Information
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rat ... Grin2a(24409)
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Description:
Biochem/physiol Actions
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Linkage
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Application
Glycine is a non-essential amino acid. It is the simplest of the amino acids and plays various roles in biology. It is structurally unique among the biological amino acids in that it does not have an asymmetric center, and thus is not chiral. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.
General description
PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.
Safety:
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR
NONH for all modes of transport