Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | Caspase-1(Cleaved-Asp210)Antibody |
| Synonyms | CASP-1;caspase-1;ICE;IL-1betaconvertingenzyme;IL-1BC;IL1BCE;interleukin-1betaconvertase;interleukin-1betaconvertingenzyme;p45 |
| Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanCaspase-1(Cleaved-Asp210). |
| ImmunogenRange | 161-210 |
| Clonality | Polyclonal |
| ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:10000 |
| Specificity | Caspase-1(Cleaved-Asp210)AntibodydetectsendogenouslevelsoffragmentofactivatedCaspase-1resultingfromcleavageadjacenttoAsp210. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingimmunogen. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | CASP1 |
| DatabaseLinks | GeneID: 834 Swiss-Prot#: P29466 OMIM#: 147678 Unigene#: Hs.2490 |
| TargetModification | Cleaved |
| ModificationSites | Asp210 |
| ApplicationImages |
| Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanlungcarcinomatissue,usingCaspase-1(Cleaved-Asp210)Antibody.Thepictureontherightisblockedwiththesynthesizedpeptide. |
| Image2 | WesternblotanalysisofextractsfromK562cells,andHepG2cellstreatedwithadriamycin,usingCaspase1(Cleaved-Asp210)antibody(#L0114). Thelaneontherightisblockedwiththesynthesizedpeptide. |