anthracenedionedihydrochloride,MitoxantronedihydrochlorideProperties:
RelatedCategories | AnalyticalStandards,Analytical/Chromatography,EPStandards,EPStandardsL-M,Pharmacopeia&MetrologicalInstitutesStandards |
Description:
Biochem/physiolActions
MitoxantroneisacytostaticanthracenedionethatintercalatesinDNAandincreasestheincidenceofdouble-strandbreaksbystABIlizingthecleavablecomplexoftopoisomeraseIIandDNA.Mitoxantronealsodisplaysbroadimmunosuppressiveactivityinhibitingproliferationofallclassesoflymphocytesandinducingapoptosisofantigen-presentingTcells.Itusedclinicallyasachemotherapeuticagentagainstleukemiasandsolidtumorsandasanimmunesystemmodulatorinmultiplesclerosis.
Caution
PleasefindSDSprovidedbyEDQMhere.
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OtherNotes
Salesrestrictionsmayapply.
Packaging
Unitquantity:60mg.Subjecttochange.TheproductisdeliveredassuppliedbytheissuingPharmacopoeia.Forthecurrentunitquantity,pleasevisittheEDQMreferencesubstancecatalogue
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Generaldescription
ThisproductisprovidedasdeliveredandspecifiedbytheissuingPharmacopoeia.Allinformationprovidedinsupportofthisproduct,includingSDSandanyproductinformationleafletshavebeendevelopedandissuedundertheAuthorityoftheissuingPharmacopoeia.ForfurtherinformationandsupportpleasegotothewebsiteoftheissuingPharmacopoeia
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Safety:
Symbol

GHS08
Hazardstatements
H340-H360
Precautionarystatements
P201-P280-P308+P313
RIDADR
NONHforallmodesoftransport