Mouse monoclonal antibody raised against human ITGA6.
Immunogen:
Recombinant protein corresponding to human ITGA6.
Host:
Mouse
Reactivity:
Human
Form:
Liquid
Purification:
Protein G purification
Isotype:
IgG1
Recommend Usage:
Flow Cytometry (1:10-1:50)Immunohistochemistry (1:10-1:50)Immunofluorescence (1:10-1:50)Western Blot (1:100-1:16000)The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (0.09% sodium azide)
Storage Instruction:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Datasheet:
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell line lysates reacted with ITGA6 monoclonal antibody (Cat # MAB12290) at 1:100-1:16000 dilution.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human skin carcinoma reacted with ITGA6 monoclonal antibody (Cat # MAB12290) at 1:10-1:50 dilution.
Immunofluorescence
Immunofluorescent staining of HepG2 cell reacted with ITGA6 monoclonal antibody (Cat # MAB12290) at 1:10-1:50 dilution.
Flow Cytometry
Flow cytometric analysis of HepG2 cells (right histogram) and a negative control cell (left histogram) reacted with ITGA6 monoclonal antibody (Cat # MAB12290) at 1:10-1:50 dilution.
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations:
integrin alpha chain, alpha 6,integrin alpha6B
Gene Pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
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