| Immunogen | Nucleifromadulthumanthymicbiopsyspecimens. | 
| Clone | LN-6 | 
| Host | Mouse | 
| Specificity | Reactswithhumanmesenchymalcellsandderivedsarcomas.Reactswithanepitopeofthecytoskeletalproteinvimentinbutunlikeothervimentinantibodies,doesnotreactwithhumanlymphoidcellsorderivedmalignancies.Reactivewithendothelium,muscle,fibroblasts,melanocytes,peripheralnerve,sertolicells,kidneymesangialcellsandtubules,osteoblastsandperiosteum,non-hematopoietictumorsofmesenchymalorigin(allsarcomas),meningiomasandmelanomas. | 
| Isotype | IgM | 
| SpeciesReactivity |  | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | AlongwiththeMICROFILaments(actins)andmicrotubules(tubulins),theintermediatefilamentsrepresentathirdclassofwell-characterizedcytoskeletalelements.Thesubunitsdisplayatissue-specificpatternofexpression.Desmin(MIM125660)isthesubunitspecificformuscleandvimentinthesubunitspecificformesenchymaltissue.[suppliedbyOMIM] | 
| GeneSymbol | - VIM
 - FLJ36605
 - Vimentin.
 - vimentin
 
  | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P08670#Vimentinsareclass-IIIintermediatefilamentsfoundinvariousnon-epithelialcells,especiallymesenchymalcells. SIZE:466aminoacids;53652Da SUBUNIT:Homopolymer.ComponentofacomplexcomposedatleastofACTB,AP2M1,AP2A1,AP2A2,MEGF10andVIM.InteractswithHCVcoreprotein. TISSUESPECIFICITY:Highlyexpressedinfibroblasts,someexpressioninT-andB-lymphocytes,andlittleornoexpressioninBurkitt"slymphomacelllines.Expressedinmanyhormone-independentmammarycarcinomacelllines. PTM:Oneofthemostprominentphosphoproteinsinvariouscellsofmesenchymalorigin.Phosphorylationisenhancedduringcelldivision,atwhichtimevimentinfilamentsaresignificantlyreorganized. SIMILARITY:SwissProt:P08670##Belongstotheintermediatefilamentfamily. | 
| MolecularWeight | 57-60kDa |