| Immunogen | SyntheticpeptidefromhumannorepinephrineTransporter. | 
| Host | Mouse | 
| Specificity | NorepinephrineTransporter,humanandnon-humanprimate. | 
| Isotype | IgG | 
| SpeciesReactivity |  | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | TheSLC6A2geneencodesanorepinephrine(noradrenaline)transporter,whichisresponsIBLeforreuptakeofnorepinephrineintopresynapticnerveterminalsandisaregulatorofnorepinephrinehomeostasis(Kimetal.,2006[PubMed17146058]).[suppliedbyOMIM] | 
| GeneSymbol |  | 
| PurificationMethod | Ascites | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P23975#Aminetransporter.Terminatestheactionofnoradrenalinebyitshighaffinitysodium-dependentreuptakeintopresynapticterminals. SIZE:617aminoacids;69332Da
 SUBUNIT:InteractswithPRKCABP.
 SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
 DISEASE:SwissProt:P23975#DefectsinSLC6A2areacauseoforthostaticintolerance(OI)[MIM:604715].OIisasyndromecharacterizedbylightheadedness,fatigue,alteredmentationandsyncope.Itisassociatedwithposturaltachycardia.Plasmanorepinephrineconcentrationisabnormallyhigh.
 SIMILARITY:SwissProt:P23975##Belongstothesodium:neurotransmittersymporter(SNF)family.
 MISCELLANEOUS:Thisproteinisthetargetofpsychomotorstimulantssuchasamphetaminesorcocaine.
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