Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
| ProductName | ALK(Phospho-Tyr1586)Antibody |
| Synonyms | ALKtyrosinekinasereceptorprecursor;Anaplasticlymphomakinase;CD246;kinaseALK |
| Immunogen | Theantiserumwasproducedagainstsynthesizedphospho-peptidederivedfromhumanALKaroundthephosphorylationsiteofTyr1586. |
| ImmunogenRange | |
| Clonality | Polyclonal |
| ApplicationDilutions | IHC:1:50~1:100ELISA:1:10000 |
| Specificity | ALK(Phospho-Tyr1586)antibodydetectsendogenouslevelsofALKonlywhenphosphorylatedatTyr1586. |
| Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
| PhysicalForm | RabbitIgGinphosphatebufferedsaline(Phospho-withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
| Storage/StABIlity | Stableat-20°Cforatleast1year. |
| NCBIGeneSymbol | ALK |
| DatabaseLinks | GeneID: 238 Swiss-Prot#: Q9UM73 OMIM#: 105590 Unigene#: Hs.654469 |
| TargetModification | Phospho |
| ModificationSites | H:Y1586,M:Y1592 |
| ApplicationImages |
| Image1 | Enzyme-LinkedImmunosorbentAssay(Phospho-ELISA)forImmunogenPhosphopeptide(Phospho-left)andNon-Phosphopeptide(Phospho-right),usingALK(Phospho-Tyr1586)Antibody |
| Image3 | Immunohistochemistryanalysisofphospho-ALK(Phospho-Tyr1586)antibodyinparaffin-embeddedhumanlungadenocarcinomatissue. |