The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
Trk B (Phospho-Tyr817) Antibody
Synonyms
BDNF/NT-3 growth factors receptor; GP145-TrkB; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
Immunogen
The antiserum was produced against synthesized phospho-peptide derived from human Trk B around the phosphorylation site of Tyr817.
Immunogen Range
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:10000
Specificity
Trk B (Phospho-Tyr817) antibody detects endogenous levels of Trk B only when phosphorylated at Tyr817.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
NTRK2
Database Links
Gene ID: 4915 Swiss-Prot #: Q16620
OMIM #: 600456 Unigene #: Hs.494312/Hs.712776
Target Modification
Phospho
Modification Sites
H:Y817, M:Y816, R:Y816
Application Images
Image 1
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Trk B (Phospho-Tyr817) Antibody
Image 2
Western blot analysis of lysates from K562 cells, using p-Thrrk B (Phospho-Tyr817) antibody.