Synonym:
Benzylpenicillin potassium salt
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CAS Number 113-98-4
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Empirical Formula (Hill Notation) C16H17KN2O4S
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Molecular Weight 372.48
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Beilstein Registry Number 3832841
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EC Number 204-038-0
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MDL number MFCD00036193
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PubChem Substance ID 24898970
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eCl@ss 34010400
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Popular Documents: Specification Sheet (PDF)
Properties:
Related Categories |
Analytical/Chromatography,
Antibacterial,
Antibiotics,
Antibiotics A to Z,
Antibiotics N-S,
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InChI Key
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IYNDLOXRXUOGIU-LQDWTQKMSA-M
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form
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powder
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potency
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1440-1680 units per mg
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solubility
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H2O: 100 mg/mL
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suitability
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meets USP testing specifications
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Mode of action
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cell wall synthesis | interferes
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antibiotic activity spectrum
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Gram-positive bacteria
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Description:
Application
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Biochem/physiol Actions
Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.
Caution
Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.
Packaging
10mu,25mu,100mu
Other Notes
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place
Safety:
Symbol

GHS07
Precautionary statements
P280
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RIDADR
NONH for all modes of transport