Sigma-Aldrich/Caffeine Melting Point Standard/PHR1095-1G/1G

• CAS Number 58-08-2

• Empirical Formula (Hill Notation) C₈H₁₀N₄O₂

• Molecular Weight 194.19

•  Beilstein Registry Number 17705

•  EC Number 200-362-1

•  MDL number MFCD00005758

•  PubChem Substance ID 329823117

Properties:

Description:

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).

Biochem/physiol Actions

A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB0976 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety:

Symbol 

  GHS07