Sigma-Aldrich/Budesonide/PHR1178-500MG/500MG

• CAS Number 51333-22-3

• Empirical Formula (Hill Notation) C₂₅H₃₄O₆

• Molecular Weight 430.53

•  EC Number 257-139-7

•  MDL number MFCD00083259

•  PubChem Substance ID 329823190

Properties:

Description:

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).

Values of analytes vary lot to lot.

Biochem/physiol Actions

Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA8997 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety: