Synonym:
5-Chloro-2-(2,4-dichlorophenoxy)phenol,
Irgasan,
Triclosan
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CAS Number 3380-34-5
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Empirical Formula (Hill Notation) C12H7Cl3O2
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Molecular Weight 289.54
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Beilstein Registry Number 2057142
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EC Number 222-182-2
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MDL number MFCD00800992
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PubChem Substance ID 329823323
Properties:
| Related Categories |
Additional Standards,
Analytical Standards,
Analytical/Chromatography,
Chromatography,
Pharmaceutical Secondary Standards,
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grade
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certified reference material
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pharmaceutical secondary standard
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InChI Key
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XEFQLINVKFYRCS-UHFFFAOYSA-N
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form
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neat
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format
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neat
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pharmacopeia traceability
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traceable to USP 1682206
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Description:
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Application
A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products. Because of its low antigenicity, irgasan is also a component of many antibacterial consumer products.
Biochem/physiol Actions
Irgasan is a broad spectrum antimicrobial agent. It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Other Notes
This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA9502 in the slot below. This is an example certificate only and may not be the lot that you receive.
Safety:
Symbol


GHS07, GHS09
Hazard statements
H315-H319-H410
Precautionary statements
P273-P305 + P351 + P338-P501