Synonym:
Atovaquone,
Mepron,
trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione
Properties:
| Related Categories |
Additional Standards,
Analytical Standards,
Analytical/Chromatography,
Chromatography,
Pharmaceutical Secondary Standards,
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grade
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certified reference material
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pharmaceutical secondary standard
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InChI Key
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KUCQYCKVKVOKAY-CTYIDZIISA-N
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packaging
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pkg of 500 mg
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pharmacopeia traceability
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traceable to PhEur Y0001572
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traceable to USP 1044651
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Description:
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).
Biochem/physiol Actions
Atovaquone is an anti-protozoal mitochondrial electron transport inhibitor; Antimalarial; Antipneumocystic, and has also been used to treat toxoplasmosis. It is an analog of protozoan mitochondrial protein ubiquinone, and acts by inhibiting the cytochrome bc(1) complex via interactions with the Rieske iron-sulfur protein and cytochrome b in the ubiquinol oxidation pocket.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA4707 in the slot below. This is an example certificate only and may not be the lot that you receive.
Safety:
RIDADR
NONH for all modes of transport
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4000-520-616
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