Synonym:
1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone,
3-Hydroxymethylchrysazine,
Aloe-emodin
-
CAS Number 481-72-1
-
Empirical Formula (Hill Notation) C15H10O5
-
Molecular Weight 270.24
-
Beilstein Registry Number 2059062
-
MDL number MFCD00017373
-
PubChem Substance ID 329831502
Properties:
| Related Categories |
Analytical Standards,
Analytical/Chromatography,
EP Standards,
EP Standards C - D,
Pharmacopeia & Metrological Institutes Standards
|
Description:
Biochem/physiol Actions
Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.
Caution
Please find SDS provided by EDQM here.
.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia
.
Other Notes
Sales restrictions may apply.
Packaging
Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue
.
Safety:
Symbol

GHS07
Hazard statements
H315-H319-H335
Precautionary statements
P305 + P351 + P338
RIDADR
NONH for all modes of transport